Z632-2648 Screening compound: 4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)pyrrolidine-1-carbonyl]benzonitrile

Z632-2648 Screening compound: 4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)pyrrolidine-1-carbonyl]benzonitrile
Z632-2648 Screening compound: 4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)pyrrolidine-1-carbonyl]benzonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound Z632-2648
4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)pyrrolidine-1-carbonyl]benzonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

Z632-2648

Molecular Formula

C17H17N3O2 (C17 H17 N3 O2)

Compound Name

4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)pyrrolidine-1-carbonyl]benzonitrile

IUPAC name

4-[2-(35-dimethyl-12-oxazol-4-yl)pyrrolidine-1-carbonyl]benzonitrile

SMILES

Cc1noc(C)c1C(CCC1)N1C(c(cc1)ccc1C#N)=O

InChI

InChI=1S/C17H17N3O2/c1-11-16(12(2)22-19-11)15-4-3-9-20(15)17(21)14-7-5-13(10-18)6-8-14/h5-8,15H,3-4,9H2,1-2H3/t15-/m0/s1

InChI Key

SWHUOEXNQFDCAC-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27640818

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

295.34

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.972

Distribution Coefficient, logD

1.972

Water Solubility, LogSw

-2.03

Polar Surface Area

55.770

Acid Dissociation Constant (pKa)

19.75

Base Dissociation Constant (pKb)

-4.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

35.30

Z632-2648 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with Z632-2648 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound Z632-2648?
Check Price and Availability of Z632-2648, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of Z632-2648 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for Z632-2648
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for Z632-2648
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of Z632-2648 available by request