ZC43-0046 Screening compound: 1-{4-[1-(cyclohexylmethyl)piperidin-4-yl]-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-5-yl}-2-methylpropan-1-one

ZC43-0046 Screening compound: 1-{4-[1-(cyclohexylmethyl)piperidin-4-yl]-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-5-yl}-2-methylpropan-1-one
ZC43-0046 Screening compound: 1-{4-[1-(cyclohexylmethyl)piperidin-4-yl]-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-5-yl}-2-methylpropan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound ZC43-0046
1-{4-[1-(cyclohexylmethyl)piperidin-4-yl]-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-5-yl}-2-methylpropan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

ZC43-0046

Molecular Formula

C22H36N4O (C22 H36 N4 O)

Compound Name

1-{4-[1-(cyclohexylmethyl)piperidin-4-yl]-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridin-5-yl}-2-methylpropan-1-one

IUPAC name

1-{4-[1-(cyclohexylmethyl)piperidin-4-yl]-3H4H5H6H7H-imidazo[45-c]pyridin-5-yl}-2-methylpropan-1-one

SMILES

CC(C)C(N(CC1)C(C2CCN(CC3CCCCC3)CC2)c2c1nc[nH]2)=O

InChI

InChI=1S/C22H36N4O/c1-16(2)22(27)26-13-10-19-20(24-15-23-19)21(26)18-8-11-25(12-9-18)14-17-6-4-3-5-7-17/h15-18,21H,3-14H2,1-2H3,(H,23,24)/t21-/m0/s1

InChI Key

KXHXAZGIFVAGQD-NRFANRHFSA-N

MDL Number (MFCD)

MFCD31957434

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.55

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.665

Distribution Coefficient, logD

1.461

Water Solubility, LogSw

-3.72

Polar Surface Area

43.248

Acid Dissociation Constant (pKa)

14.25

Base Dissociation Constant (pKb)

9.60

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

81.82

ZC43-0046 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS BBB Library (22607 compounds)

CNS MPO Library (28609 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
  • Mimetics
  • Cyclic compounds
  • Mimetics
Therapeutical areas:
  • Nervous system
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with ZC43-0046 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound ZC43-0046?
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What is the minimum amount of ZC43-0046 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for ZC43-0046
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for ZC43-0046
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of ZC43-0046 available by request