ZC43-0080 Screening compound: cyclopropyl{4-[5-(tetrahydro-2H-pyran-4-ylmethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-4-yl]piperidino}methanone

ZC43-0080 Screening compound: cyclopropyl{4-[5-(tetrahydro-2H-pyran-4-ylmethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-4-yl]piperidino}methanone
ZC43-0080 Screening compound: cyclopropyl{4-[5-(tetrahydro-2H-pyran-4-ylmethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-4-yl]piperidino}methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound ZC43-0080
cyclopropyl{4-[5-(tetrahydro-2H-pyran-4-ylmethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-4-yl]piperidino}methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

ZC43-0080

Molecular Formula

C21H32N4O2 (C21 H32 N4 O2)

Compound Name

cyclopropyl{4-[5-(tetrahydro-2H-pyran-4-ylmethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-4-yl]piperidino}methanone

IUPAC name

1-cyclopropanecarbonyl-4-{5-[(oxan-4-yl)methyl]-3H4H5H6H7H-imidazo[45-c]pyridin-4-yl}piperidine

SMILES

O=C(C1CC1)N(CC1)CCC1C1N(CC2CCOCC2)CCc2c1[nH]cn2

InChI

InChI=1S/C21H32N4O2/c26-21(17-1-2-17)24-8-3-16(4-9-24)20-19-18(22-14-23-19)5-10-25(20)13-15-6-11-27-12-7-15/h14-17,20H,1-13H2,(H,22,23)/t20-/m0/s1

InChI Key

YNNDBDOOLIMNBY-FQEVSTJZSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.811

Distribution Coefficient, logD

0.454

Water Solubility, LogSw

-2.09

Polar Surface Area

51.574

Acid Dissociation Constant (pKa)

14.25

Base Dissociation Constant (pKb)

8.74

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

80.95

ZC43-0080 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with ZC43-0080 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound ZC43-0080?
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What is the minimum amount of ZC43-0080 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for ZC43-0080
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for ZC43-0080
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of ZC43-0080 available by request