ZC46-0062 Screening compound: 1-{7-cyclopropanecarbonyl-8-phenyl-5H,6H,7H,8H-imidazo[1,2-a]pyrazine-2-carbonyl}piperidine

ZC46-0062 Screening compound: 1-{7-cyclopropanecarbonyl-8-phenyl-5H,6H,7H,8H-imidazo[1,2-a]pyrazine-2-carbonyl}piperidine
ZC46-0062 Screening compound: 1-{7-cyclopropanecarbonyl-8-phenyl-5H,6H,7H,8H-imidazo[1,2-a]pyrazine-2-carbonyl}piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound ZC46-0062
1-{7-cyclopropanecarbonyl-8-phenyl-5H,6H,7H,8H-imidazo[1,2-a]pyrazine-2-carbonyl}piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

ZC46-0062

Molecular Formula

C22H26N4O2 (C22 H26 N4 O2)

Compound Name

1-{7-cyclopropanecarbonyl-8-phenyl-5H,6H,7H,8H-imidazo[1,2-a]pyrazine-2-carbonyl}piperidine

IUPAC name

1-{7-cyclopropanecarbonyl-8-phenyl-5H6H7H8H-imidazo[12-a]pyrazine-2-carbonyl}piperidine

SMILES

O=C(C1CC1)N(CCn1c2nc(C(N3CCCCC3)=O)c1)C2c1ccccc1

InChI

InChI=1S/C22H26N4O2/c27-21(17-9-10-17)26-14-13-25-15-18(22(28)24-11-5-2-6-12-24)23-20(25)19(26)16-7-3-1-4-8-16/h1,3-4,7-8,15,17,19H,2,5-6,9-14H2/t19-/m1/s1

InChI Key

AXLVJEWPFDTDDD-LJQANCHMSA-N

MDL Number (MFCD)

MFCD31956594

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

378.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.884

Distribution Coefficient, logD

2.884

Water Solubility, LogSw

-2.93

Polar Surface Area

45.004

Acid Dissociation Constant (pKa)

22.33

Base Dissociation Constant (pKb)

1.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

ZC46-0062 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

GABA Library (7115 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Ion Channels Focused Library (26372 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Eye
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Mimetics
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with ZC46-0062 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound ZC46-0062?
Check Price and Availability of ZC46-0062, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of ZC46-0062 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for ZC46-0062
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for ZC46-0062
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of ZC46-0062 available by request