ZC47-0157 Screening compound: 2-methyl-4-[1-(2-phenoxyethyl)piperidin-4-yl]-N-[(pyrimidin-4-yl)methyl]pyrimidine-5-carboxamide

ZC47-0157 Screening compound: 2-methyl-4-[1-(2-phenoxyethyl)piperidin-4-yl]-N-[(pyrimidin-4-yl)methyl]pyrimidine-5-carboxamide
ZC47-0157 Screening compound: 2-methyl-4-[1-(2-phenoxyethyl)piperidin-4-yl]-N-[(pyrimidin-4-yl)methyl]pyrimidine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound ZC47-0157
2-methyl-4-[1-(2-phenoxyethyl)piperidin-4-yl]-N-[(pyrimidin-4-yl)methyl]pyrimidine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

ZC47-0157

Molecular Formula

C24H28N6O2 (C24 H28 N6 O2)

Compound Name

2-methyl-4-[1-(2-phenoxyethyl)piperidin-4-yl]-N-[(pyrimidin-4-yl)methyl]pyrimidine-5-carboxamide

IUPAC name

2-methyl-4-[1-(2-phenoxyethyl)piperidin-4-yl]-N-[(pyrimidin-4-yl)methyl]pyrimidine-5-carboxamide

SMILES

Cc(nc1)nc(C2CCN(CCOc3ccccc3)CC2)c1C(NCc1ncncc1)=O

InChI

InChI=1S/C24H28N6O2/c1-18-26-16-22(24(31)27-15-20-7-10-25-17-28-20)23(29-18)19-8-11-30(12-9-19)13-14-32-21-5-3-2-4-6-21/h2-7,10,16-17,19H,8-9,11-15H2,1H3,(H,27,31)

InChI Key

DVTJJQOUIPDKKX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31958048

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.53

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.619

Distribution Coefficient, logD

1.895

Water Solubility, LogSw

-2.79

Polar Surface Area

75.671

Acid Dissociation Constant (pKa)

10.66

Base Dissociation Constant (pKb)

8.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

ZC47-0157 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Mimetics
Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with ZC47-0157 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound ZC47-0157?
Check Price and Availability of ZC47-0157, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of ZC47-0157 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for ZC47-0157
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for ZC47-0157
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of ZC47-0157 available by request